About Us

Delcath Systems, Inc. is an interventional oncology company focused on the treatment of primary and metastatic liver cancers. The company’s proprietary products are HEPZATO KIT™ (melphalan) for Injection/Hepatic Delivery System (HDS) and CHEMOSAT® Hepatic Delivery System for Melphalan percutaneous hepatic perfusion (PHP).

 

Our Mission

To deliver therapies for the treatment of patients with primary and metastatic cancers to the liver through the use/application of an innovative procedure of vascular isolation of the liver, focused delivery of therapy and filtration of excess drug to improve clinical outcomes for patients while reducing drug-related side effects.

 

Our Team

At Delcath Systems we have an exceptional team of individuals, who each bring with them a personal desire to change the world for people with rare and life-threatening liver conditions.

Gerard Michel

CHIEF EXECUTIVE OFFICER

Gerard Michel

CHIEF EXECUTIVE OFFICER

Mr. Michel has over 30 years of experience in the pharmaceutical and medical technology industries across multiple functional areas.

Prior to joining the Company, Mr. Michel was Chief Financial Officer of Vericel Corp., a biopharmaceutical company, since June 2014 where he was a key member of the management team which integrated a transformative acquisition and revised the company’s business model from a research focused company to a fully integrated, profitable commercial business. Mr. Michel also served as Chief Financial Officer and Vice President, Corporate Development of Biodel Inc., a specialty biopharmaceutical company focused on the treatment of diabetes, from November 2007 to May 2014, and Chief Financial Officer and Vice President of Corporate Development of NPS Pharmaceuticals Inc., a biopharmaceutical company focused on treatment options for patients with gastrointestinal and endocrine disorders, from August 2002 to November 2007. Prior to that, Mr. Michel was a Principal at Booz Allen Hamilton Inc. and also held a variety of commercial roles at both Lederle Labs and Wyeth Labs. Mr. Michel holds an M.S. in Microbiology from the University of Rochester School of Medicine, an M.B.A. from the Simon School of Business, and a B.S. in both Biology and Geology from the University of Rochester.

Martha S. Rook, PhD

CHIEF OPERATING OFFICER

Martha S. Rook, PhD

CHIEF OPERATING OFFICER

Martha S. Rook, Ph.D., is an experienced industry leader who brings more than 25 years of academic and industry experience in molecular biology, diagnostics development, biologics process development and biologics manufacturing. She joined Delcath in March of 2024 from insitro where she served as a Chief Technical Operations Officer and was responsible for core research services, facilities and laboratory operations, quality and project and portfolio management. Prior to insitro, she was with Sigilon Therapeutics, where she served as Chief Technical Operations Officer and was responsible for the analytics, manufacturing, supply chain and quality organizations producing a biologic-device combination product.

Martha’s experience also includes 13 years at MilliporeSigma, where she held a variety of roles, ultimately serving as vice president and head of the Gene Editing & Novel Modalities Business and led a team developing and providing tools and services for cell and gene therapies from discovery to manufacturing. Martha received her Ph.D. in biochemistry from MIT and holds a B.S. in chemistry from Texas A&M University. She pursued postdoctoral studies in neuroscience as a Lefler Fellow at Harvard Medical School’s Center for Neurologic Diseases.

Vojislav “Vojo” Vukovic, MD, MSc, PhD

CHIEF MEDICAL OFFICER

Vojislav “Vojo” Vukovic, MD, MSc, PhD

CHIEF MEDICAL OFFICER

Dr. Vukovic is an experienced drug development executive with a distinguished career in cancer research and global clinical development. His experience spans early- to late-stage clinical development projects across multiple anticancer modalities and tumor types and global medical affairs programs supporting several commercial oncology drugs. He has held the position of Senior Vice President and Chief Medical Officer at Aileron Therapeutics, Taiho Oncology Inc, and Synta Pharmaceuticals Inc, overseeing various facets of clinical development, medical affairs, and corporate strategy.

Dr. Vukovic earned his MD from the University of Sarajevo in Bosnia and Herzegovina and an MSc in radiation biology and a PhD in tumor biology from the University of Toronto in Canada. His work has been published in several high-impact scientific journals, and he is a member of the American Association for Cancer Research, the American Society of Clinical Oncology, the American Society of Hematology, and the European Society for Medical Oncology.

Johnny John, MD

SVP CLINICAL OPERATIONS AND
MEDICAL AFFAIRS

Johnny John, MD

SVP CLINICAL OPERATIONS AND MEDICAL AFFAIRS

Dr. John has worked in oncology drug development and clinical trials for over 15 years.

Prior to joining Delcath he worked in Clinical Trial Operations at InVentiv Health. Among the clinical programs he worked on there were the trials that resulted in the FDA approval of Ipilimumab. Prior to InVentiv Health, Dr. John spent over 11 years in clinical practice. He received his medical degree from Mangalore University, India and postgraduate training at the University of Illinois.

Kevin Muir

GENERAL MANAGER
INTERVENTIONAL ONCOLOGY

Kevin Muir

GENERAL MANAGER INTERVENTIONAL ONCOLOGY

Mr. Muir joins Delcath Systems with 20 years of sales and marketing experience in the biotherapeutics and medical technology industries.

Before joining Delcath, Mr. Muir was Director of U.S. Sales for the Interventional Oncology business unit at BTG, where he played a key role in the success of TheraSphere™ (custom ordered micro-embolic 90Y radiation radio isotope-therapy). Prior to that he was Director of Sales at ClearFlow Inc. and Aragon Surgical. Mr. Muir also held leadership sales roles at Kensey Nash Corporation, Kyphon, and Genzyme Biosurgery. Prior to his career in industry, Mr. Muir served as a Field Artillery officer in the U.S. Army. He completed his BS in Management Systems Engineering at the United States Military Academy at West Point where he was a member of the West Point Cadets Football Team.

David Hoffman

General Counsel, Corporate Secretary & Chief Compliance Officer

David Hoffman

GENERAL COUNSEL, CORPORATE SECRETARY & CHIEF COMPLIANCE OFFICER

David brings over 20 years of experience advising biotechnology companies with a focus on the commercialization of therapies.

Most recently, he served as Associate General Counsel and Chief Compliance Officer at Vericel Corporation, where he was responsible for legal and compliance matters and supported the launch and growth of products in the advanced cell therapy and biologics space. His background and counsel will be a crucial asset as we continue to progress on our mission to commercialize new therapies to treat cancers of the liver.

Sandra Pennell

SENIOR VICE PRESIDENT OF FINANCE

Sandra Pennell

SENIOR VICE PRESIDENT OF FINANCE

Sandra has 20+ plus years in a variety of financial areas including complete oversight of the Finance and Accounting function specializing in SEC reporting, equity raises, FP&A, all accounting functions in addition to treasury experience related to debt financings and internal investment decisions. She previously held the position of VP, Finance at Invivyd, Inc. and prior to that she was the VP & Corporate Controller, Principal Accounting Officer at Vericel Corporation. Sandra earned a Bachelor and Master of Science in Accountancy from University of Illinois at Urbana-Champaign – College of Business.

Board of Directors

Bridget Martell, MA, MD

Director

Bridget Martell, MA, MD

DIRECTOR

Dr. Bridget Martell was appointed to Delcath Systems’ Board of Directors in May 2024. She brings a wealth of experience from her roles in senior management and as a director at multiple biotechnology companies. Currently, she serves as an independent director at Aligos Therapeutics and Achieve Life Sciences. She previously held director roles at POINT Biopharma Global and Ayala Pharmaceuticals. Dr. Martell is also a Biotechnology Operating Partner at Two Bear Capital and founded BAM Consultants. Her past executive roles include President and CEO of Artizan Biosciences and Chief Medical Officer for various biotech companies.

Dr. Martell holds a B.S. in Microbiology from Cornell University, an M.A. in Molecular Immunology from Boston University, and an M.D. from Chicago Medical School. She completed her internal medicine residency and served as Chief Resident at Yale University, where she continues to engage as an Entrepreneur In Residence at Yale Ventures.

John R. Sylvester

Chairman of the Board

John R .Sylvester

CHAIRMAN OF THE BOARD

John R. Sylvester most recently served as CEO of Curium Pharma’s SPECT and International businesses. Prior to that he served as Chief Commercial Officer of BTG plc, which he joined in 2011 and had roles leading both their Interventional Oncology and Interventional Vascular businesses as well as a period as Chief Development Officer accountable for Strategy, M&A and Market access. This culminated in an exit to Boston Scientific for $4.2 billion. Prior to BTG, John was Managing Director of Biocompatibles plc, building their Interventional Oncology business which led to a successful exit to BTG for £166.0 million. John joined Biocompatibles following a period as the Vice President of Marketing for Baxter Healthcare’s $750.0 million European Medication Delivery business based in Brussels then Zurich accountable for six strategic business units incorporating drugs, devices and drug device combinations. Before this, John held a number of senior commercial roles in the industrial sector. Immediately prior to Baxter Healthcare, John was the General Manager of a Minerals company with $4.0 billion of assets on three continents, $500.0 million of sales and 1,500 employees. John graduated with joint honours in Biochemistry and Applied Molecular Biology from the University of Manchester Institute of Science and Technology (U.M.I.S.T.).

 

Elizabeth Czerepak

Director

Elizabeth Czerepak

DIRECTOR

Elizabeth currently serves as Chief Financial Officer for Mirror Biologics, Inc., a private clinical stage oncology company. She previously served as Chief Financial Officer for several other public and private biopharma companies, where she was successful in helping achieve public listings for commercial-stage Scilex Holding, Inc. through a SPAC merger, Altimmune, Inc. via merger with a public company, and an IPO for Cancer Genetics, Inc. Elizabeth began her career serving in senior and executive level positions for 18 years at BASF (Knoll) Pharmaceuticals, Hoffmann-La Roche, and Merck & Co. Her major pharma executive level experience includes M&A, licensing, business development and finance. She received a B.A., magna cum laude in Spanish and Mathematics Education from Marshall University and an MBA from Rutgers University.

 

Steven Salamon

Director

Steven Salamon

DIRECTOR

Steven Salamon is a co-founder and Portfolio Manager at Rosalind Advisors, Inc., a life sciences focused investment manager established in 2006 (“Rosalind Advisors”).

Rosalind Advisors is the investment manager for the Rosalind Funds. Mr. Salamon holds a MBA from the Ivey Business School and an Engineering Physics degree from the University of Toronto. Prior to co-founding Rosalind Advisors, Mr. Salamon worked as an equity analyst at HSBC Securities and RBC Capital Markets (formerly RBC Dominion Securities).

Gil Aharon, PhD

Director

Gil Aharon, PhD

DIRECTOR

Dr. Gilad Aharon is a co-founder and Portfolio Manager at Rosalind Advisors.

Dr. Aharon holds a Ph.D. in Biophysics and Molecular Biology from the University of Toronto. Prior to co-founding Rosalind Advisors, Dr. Aharon worked as an equity analyst at Infinium Securities Inc.

Gerard Michel

Chief Executive Officer

Gerard Michel

CHIEF EXECUTIVE OFFICER

Mr. Michel has over 30 years of experience in the pharmaceutical and medical technology industries across multiple functional areas.

Prior to joining the Company, Mr. Michel was Chief Financial Officer of Vericel Corp., a biopharmaceutical company, since June 2014 where he was a key member of the management team which integrated a transformative acquisition and revised the company’s business model from a research focused company to a fully integrated, profitable commercial business. Mr. Michel also served as Chief Financial Officer and Vice President, Corporate Development of Biodel Inc., a specialty biopharmaceutical company focused on the treatment of diabetes, from November 2007 to May 2014, and Chief Financial Officer and Vice President of Corporate Development of NPS Pharmaceuticals Inc., a biopharmaceutical company focused on treatment options for patients with gastrointestinal and endocrine disorders, from August 2002 to November 2007. Prior to that, Mr. Michel was a Principal at Booz Allen Hamilton Inc. and also held a variety of commercial roles at both Lederle Labs and Wyeth Labs. Mr. Michel holds an M.S. in Microbiology from the University of Rochester School of Medicine, an M.B.A. from the Simon School of Business, and a B.S. in both Biology and Geology from the University of Rochester.